Publication References

John F. Alderete, Ph.D.

2023

  1. Point-of-Care Diagnostic for Trichomonas vaginalis, the Most Prevalent, Non-Viral Sexually Transmitted Infection - Pathogens

2021

  1. Altering Trichomonas vaginalis Codons Enhances Expression of the Trichomonad P270 Repeat Element in Escherichia coli.

  2. An mRNA-Binding Protein of The Ancient Protist Trichomonas vaginalis

  3. Recombinant Protein of Immunogenic Metabolic Enzyme Epitopes of Trichomonas vaginalis are Common to Humans and Microorganisms

  4. . Localization of the phenotypically varying P270 protein on dsRNA virus-positive and negative Trichomonas vaginalis isolates. Amer. J. Biomed. Sci. & Res.14(2);199-209.

  5. Alderete, J.F. 2021. OxyraseTM for optimal growth of Trichomonas vaginalis isolates. Amer. J. Biomed. Sci. & Res. 14(6):551-0556.

2020

  1. Co-author with STEM Task Force Members, 2020. “Rethinking Policy and Practice for STEM Education: New Hispanic Perspectives,” Hispanic Association of Colleges and Universities, Report Released to Public and Government Agencies, February 28, 2020.

  2. Advancing Prevention of STIs by Developing Specific Serodiagnostic Targets: Trichomonas vaginalis as a Model

2019

  1. Trichomonas vaginalis infection and prostate‐specific antigen concentration: Insights into prostate involvement and prostate disease risk

2017

  1. Trichomonas vaginalis infection and risk of prostate cancer: associations by disease aggressiveness and race/ethnicity in the PLCO Trial

  2. Epitopes within recombinant α-actinin protein is serodiagnostic target for Trichomonas vaginalis sexually transmitted infections

2016

  1. Sexually transmitted infections, benign prostatic hyperplasia and lower urinary tract symptom-related outcomes: results from the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial

  2. A prospective study of Trichomonas vaginalis and prostate cancer risk among African-American men

2015

  1. Sequestration of host-CD59 as potential immune evasion strategy of Trichomonas vaginalis

  2. Persistence of Trichomonas vaginalis serostatus in men over time

2014

  1. Determination of internal transcribed spacer regions (ITS) in Trichomonas vaginalis isolates and differentiation among Trichomonas species

2013

  1. Prospective study of effect modification by Toll-like receptor 4 variation on the association between Trichomonas vaginalis serostatus and prostate cancer

  2. Epitopes of the Highly Immunogenic Trichomonas vaginalis α-Actinin Are Serodiagnostic Targets for Both Women and Men

  3. Identification, characterization, and synthesis of peptide epitopes and a recombinant six-epitope protein for Trichomonas vaginalis serodiagnosis

2012

  1. Trichomonosis, a Common Curable STI, and Prostate Carcinogenesis—A Proposed Molecular Mechanism

  2. Comparative Transcriptomic and Proteomic Analyses of Trichomonas vaginalis following Adherence to Fibronectin

2011

  1. Trichomonas vaginalis, Reproductive Health, and a Minority Scientist's Experiences.

2009

  1. Glyceraldehyde-3-Phosphate Dehydrogenase Is a Surface-Associated, Fibronectin-Binding Protein of Trichomonas vaginalis

  2. Trichomonosis and subsequent risk of prostate cancer in the Prostate Cancer Prevention Trial

  3. Correlates Of Sexually Transmitted Infection Histories In A Cohort Of American Male Health Professionals

  4. Prospective Study of Trichomonas vaginalis Infection and Prostate Cancer Incidence and Mortality: Physicians’ Health Study

  5. Genetic identity and differential gene expression between Trichomonas vaginalis and Trichomonas tenax

  6. Examination for double-stranded RNA viruses in Trichomonas gallinae and identification of a novel sequence of a Trichomonas vaginalis virus

  7. Comparative analyses among the Trichomonas vaginalis, Trichomonas tenax, and Tritrichomonas foetus 5S ribosomal RNA genes

2008

  1. Immunogenic and Plasminogen-Binding Surface-Associated α-Enolase of Trichomonas vaginalis

  2. Polyamine depletion down-regulates expression of the Trichomonas vaginalis cytotoxic CP65, a 65-kDa cysteine proteinase involved in cellular damage

  3. First molecular characterisation of hydrogenosomes in the protozoan parasite Histomonas meleagridis

2007

  1. The proteins secreted by Trichomonas vaginalis and vaginal epithelial cell response to secreted and episomally expressed AP65

  2. Characterization of the Trichomonas vaginalis surface-associated AP65 and binding domain interacting with trichomonads and host cells

  3. Antisense RNA decreases AP33 gene expression and cytoadherence by T. vaginalis

2006

  1. Trichomonas vaginalis promotes apoptosis of human neutrophils by activating caspase-3 and reducing Mcl-1 expression

  2. Plasma Antibodies against Trichomonas vaginalis and Subsequent Risk of Prostate Cancer

  3. A novel surface protein of Trichomonas vaginalis is regulated independently by low iron and contact with vaginal epithelial cells

2005

  1. Trichomonas vaginalis Polyamine Metabolism Is Linked to Host Cell Adherence and Cytotoxicity

  2. Trichomonas vaginalis perturbs the junctional complex in epithelial cells

  3. Heterologous expression in Tritrichomonas foetus of functional Trichomonas vaginalis AP65 adhesin

  4. Heterogeneity in extracellular nucleotide hydrolysis among clinical isolates of Trichomonas vaginalis

  5. Adherence to Human Vaginal Epithelial Cells Signals for Increased Expression of Trichomonas vaginalis Genes

2004

  1. Silencing the AP65 gene reduces adherence to vaginal epithelial cells by Trichomonas vaginalis

  2. Heme-iron increases levels of AP65-mediated adherence by Trichomonas vaginalis

2003

  1. Trichomonas vaginalis: evaluating capsid proteins of dsRNA viruses and the dsRNA virus within patients attending a sexually transmitted disease clinic

  2. Iron and contact with host cells induce expression of adhesions on surface of Trichomonas vaginalis

2002

  1. Visualization of new virus-like-particles in Trichomonas vaginalis

  2. Virus in Trichomonas—an ultrastructural study

  3. Trichomonas vaginalis: observation of coexistence of multiple viruses in the same isolate

  4. The complex fribonectin - Trichomonas vaginalis interactions and Trichomonosis

  5. Double-Stranded RNA Viral Infection of Trichomonas vaginalis Infecting Patients Attending a Sexually Transmitted Diseases Clinic

2001

  1. Trichomonas vaginalis Has Two Fibronectin-Like Iron-Regulated Genes

  2. Structure and division of the Golgi complex in Trichomonas vaginalis and Tritrichomonas foetus

  3. Enzymes on microbial pathogens and Trichomonas vaginalis: molecular mimicry and functional diversity

  4. Binding of fibronectin by Trichomonas vaginalis is influenced by iron and calcium

2000

  1. Book Review: Digging for Pathogens. Ancient Emerging Diseases— Their Evolutionary, Anthropological and Archaeological Context. The Center for the Study of Emerging Diseases.

  2. Biology of trichomonosis

1999

  1. The Trichomonas vaginalis phenotypically varying P270 immunogen is highly conserved except for numbers of repeated elements

  2. Trichomonas vaginalis interactions with fibronectin and laminin

  3. Trichomonas vaginalis, A Model Mucosal Parasite

  4. Resolution of Six Chromosomes of Trichomonas vaginalis and Conservation of Size and Number Among Isolates

  5. Iron Modulates Phenotypic Variation and Phosphorylation of P270 in Double-Stranded RNA Virus-Infected Trichomonas vaginalis

  6. Book Review: DIGGING FOR PATHOGENS: Ancient Emerging Diseases—Their Evolutionary, Anthropological and Archaeological Context

1998

  1. Specific Parasitism of Purified Vaginal Epithelial Cells by Trichomonas vaginalis

  2. Only two of the Trichomonas vaginalis triplet AP51 adhesins are regulated by iron

  3. Molecular analysis of the gene encoding the immunodominant phenotypically varying P270 protein of Trichomonas vaginalis

  4. Characterization of Trichomonas vaginalis AP33 adhesin and cell surface interactive domains

1997

  1. Trichomonas vaginalis Phenotypic Variation Occurs Only Among Trichomonads Infected With The Double-Stranded Rna Virus

  2. Involvement of dsRNA virus in the protein composition and growth kinetics of host Trichomonas vaginalis

1996

  1. Trichomonas vaginalis Adhesin Proteins Displa Y Molecular Mimicry To Metabolic Enzymes

  2. Molecular characterization of a third malic enzyme-like AP65 adhesion gene of Trichomonas vaginalis

1995

  1. Two Trichomonas vaglialis Surface Proteinases Bind to Host Epithelial Cells and Are Related to Levels of Cytoadherence and Cytotoxicity

  2. The Mechanisms and Molecules Involved in Cytoadherence and Pathogenesis of Trichomonas vaginalis

  3. Iron mediates Trichomonas vaginalis resistance to complement lysis

  4. Cloning and molecular characterization of two genes encoding adhesion proteins involved in Trichomonas vaginalis cytoadherence

  5. Analysis for Adhesins and Specific Cytoadhesion of Trichomonas vaginalis

1994

  1. Identification of Fibronectin as a Receptor for Bacterial Cytoadherence

1993

  1. Signaling of Trichomonas vaginalis for amoeboid transformation and adhesion synthesis follows cytoadherence

1992

  1. Proteinases of Trichomonas vaginalis: antibody response in patients with urogenital trichomoniasis

  2. Molecular basis of host epithelial cell recognition by Trichomonas vaginalis

  3. Iron regulates growth of Trichomonas vaginalis and the expression of immunogenic trichomonad proteins

1991

  1. Vaginal antibody of patients with trichomoniasis is to a prominent surface immunogen of Trichomonas vaginalis

  2. The Phenotypically Variable Surface Protein of Trichomonas vaginalis Has a Single, Tandemly Repeated Immunodominant Epitope

  3. Antibody in sera of patients infected with Trichomonas vaginalis is to trichomonad proteinases

1990

  1. Specific Erythrocyte Binding is an Additional Nutrient Acquisition System for Trichomonas vaginalis

  2. Properties of Trichomonas vaginalis grown under chemostat controlled growth conditions

  3. Characterization of Trichomonas vaginalis haemolysis

  4. Analysis of the Proteinases of Representative Trichomonas vaginalis Isolates

1989

  1. Serum lipoprotein binding by Treponema pallidum: possible role for proteoglycans

  2. Trichomonas vaginalis Surface Proteinase Activity Is Necessary for Parasite Adherence to Epithelial Cells

1988

  1. Monoclonal-Antibody-Based Enzyme-Linked Immunosorbent Assay for Trichomonas vaginalis

  2. Does lactobacillus vaccine for trichomoniasis, Solco Trichovac, induce antibody reactive with Trichomonas vaginalis?

  3. Alternating Phenotypic Expression of Two Classes of Trichomonas vaginalis Surface Markers

  4. Affinities of Treponema pallidum for human lactoferrin and transferrin

1987

  1. Trichomonas vaginalis Phenotypic Variation Occurs Only Among Trichomonads Infected With The Double-Stranded RNA Virus

  2. Trichomonas vaginalis NYH286 Phenotypic Variation May Be Coordinated for a Repertoire of Trichomonad Surface Immunogens

  3. Phenotypes and Protein-Epitope Phenotypic Variation among Fresh Isolates of Trichomonas vaginalis

  4. Molecular cloning of Treponema pallidum outer envelope fibronectin binding proteins, P1 and P2

  5. Identity of Treponema pallidum subsp. pallidum polypeptides: Correlation of sodium dodecyl sulfate-polyacrylamide gel electrophoresis results from different laboratories

  6. Cloning structural genes for Treponema pallidum immunogens and characterization of recombinant treponema surface protein, P2* (P2 star)

1986

  1. Trichomonas vaginalis: Electrophoretic Analysis and Heterogeneity among Isolates Due to High-Molecular-Weight Trichomonad Proteins

  2. Phenotypic Variation and Diversity among Trichomonas vaginalis Isolates and Correlation of Phenotype with Trichomonal Virulence Determinants

  3. Monoclonal antibody to a major glycoprotein immunogen mediates differential complement-independent lysis of Trichomonas vaginalis

  4. Monoclonal Antibody to a Major Surface Glycoprotein Immunogen Differentiates Isolates and Subpopulations of Trichomonas vaginalis

  5. Localization of the Ganglioside-binding Site of Fibronectin

  6. Isolation of a Treponema Pallidum gene encoding immunodominant outer envelope protein P6, which reacts with sera from patients at different stages of Syphilis

  7. Enhanced Levels of Attachment of Fibronectin-Primed Treponema pallidum to Extracellular Matrix

1985

  1. Putative Treponema pallidum Cytadhesins Share a Common Functional Domain

  2. Fibronectin Tetrapeptide Is Target For Syphilis Spirochete Cytadherence

  3. Fibronectin Mediates Treponema pallidum Cytadherence Through Recognition of Fibronectin Cell-Binding Domain

1984

  1. Trichomonas vaginalis is Dependent on Uptake and Degradation of Human Low Density Lipoproteins

  2. Soluble Trichomonas vaginalis Antigens in Cell-Free Culture Supernatants

  3. Pathogenic Trichomonas vaginalis cytotoxicity to cell culture monolayers

  4. Iron Uptake and Increased Intracellular Enzyme Activity Follow Host Lactoferrin Binding by Trichomonas vaginalis Receptors

  5. Enzyme linked immunosorbent assay for detecting antibody to Trichomonas vaginalis

  6. Selective Acquisition of Plasma Proteins by Trichomonas vaginalis and Human Lipoproteins as a Growth Requirement For This Species

1983

  1. Treponema pallidum receptor for binding proteins interact with Fibronectin

  2. The Biology of Treponema pallidum and Syphilis

  3. Enzyme-linked immunosorbent assay for the detection of serum antibody to outer membrane proteins of Treponema pallidum

  4. Acquisition of alpha 1-Antitrypsin by a pathogenic strain of Trichomonas vaginalis

1982

  1. Host plasma proteins on the surface of pathogenic Trichomonas vaginalis

  2. Analysis of serum IgG against Treponema pallidum protein antigens in experimentally infected rabbits

1981

  1. Analysis of serum IgG against Treponema pallidum protein antigens in experimentally infected rabbits

1980

  1. Surface Characterization of Virulent Treponema pallidum

1979

  1. Surface-Associated Host Proteins on Virulent Treponema pallidum

1978

  1. Purification and Chemical Characterization of the Heat-Stable Enterotoxin Produced by Porcine Strains of Enterotoxigenic Escherichia coli

1977

  1. Repression of Heat-Stable Enterotoxin Synthesis in Enterotoxigenic Escherichia coli

  2. Nutrition and Enterotoxin Synthesis by Enterotoxigenic Strains of Escherichia coli: Defined Medium for Production of Heat-Stable Enterotoxin

1975

The Effect of Host Adrenalectomy on the Physiology of Trypanosoma rhodesiense