α-Actinin (106.2-kDa)

HA423

1. Cancer Epidemiol. Biomarkers Prev. 15:939-945, 2006. PMCID: 16702374

2. J. Nat. Cancer Inst. 101:1-6, 2009. PMCID: 19741211

3. J. Clin. Microbiol. 51:2483-2490, 2013. Doi: 10.1128/JCM.00582-13. Epub 2013 Apr 24. PMCID: 23616456

4. PLoS Pathogens, Aug;8(8):e1002801, Epub 2012 August 9. PMCID: 22912571

• The discovery that HA423 reacts to α-actinin and that α-actinin can be used to screen large numbers of men and women for serum antibody.

• The discovery of a possible relationship between seropositivity to α-actinin and prostate cancer development and progression.

• The discovery showing that the protein α-actinin detected by MAb HA423 was a serodiagnostic target.

15B, 67B, 68B, 74B

1. Heliyon. 3:e00237, 2017

• MAbs to a new recombinant construct of α-actinin reaffirm α-actinin as a perfect diagnostic target detecting IgG in serum of patients.